Christoph Juchem

His long-term goal as a physicist is to realize the full potential of magnetic resonance spectroscopy (MRS) as a diagnostic tool. His clinical long-term goal is to understand the role that neurochemicals play in the protection of the human central nervous system (CNS) or, alternatively, how dysfunction promotes vulnerability towards neurodegenerative and neuro-immunological diseases.

Reliable quantification of biochemicals with in vivo MRS relies on excellent spectral data quality, processing and quantification capability. In his research, he has optimized critical aspects of the measurement pipeline including experimental conditions (e.g. B0 shimming), MRS sequences (e.g. ‘ghost’ removal) and quantification (e.g. simulation of realistic basis spectra for linear combination modeling). He furthermore developed and disseminated the freeware INSPECTOR user-tool as a one-stop-shop solution for processing, quantification and quality assessment of in vivo MRS data (200+ downloads since 2017).

Dr. Juchem has more than 20 years of experience in developing and conducting in vivo MR experiments at 3.0-11.7 Tesla field in humans and animal models and has demonstrated his scientific expertise in 50+ publications, book chapters and patents, as reviewer for 20+ scientific journals and as grant reviewer for 8 national research societies. He has served as Co-Director of Yale University's 7T Brain MR Spectroscopy Core, Chair of the ISMRM Engineering Study group, member of the ISMRM Annual Meeting Program Committee (AMPC). He has served on the editorial board of NMR in Biomedicine and as Secretary of the ISMRM MR Spectroscopy Study Group, to be Chair in 2023.

Research Areas

• Biomedical Imaging
• Medical Devices and Systems
• Biomedical Image Analysis