About the Study

Journal: Nature Nanotechnology

Title: “Selective targeting of visceral adiposity by polycation nanomedicine.”

Authors : Qianfen Wan (1)†, Baoding Huang (7,2)†, Tianyu Li (2), Yang Xiao (2), Ying He (1), Wen Du (3), Branden Z. Wang (1), Gregory F. Dakin (4), Michael Rosenbaum (3,5), Marcus D. Goncalves (6), Shuibing Chen (4), Kam W. Leong (2), Li Qiang (1)

  1. Naomi Berrie Diabetes Center and Department of Pathology and Cell Biology, Columbia University
  2. Department of Biomedical Engineering, Columbia University
  3. Department of Medicine, Columbia University
  4. Department of Surgery, Weill Cornell Medicine  
  5. Department of Pediatrics, Columbia University
  6. Department of Medicine, Department of Surgery, Weill Cornell Medicine
  7. Department of Orthopedic Surgery, The Sixth Affiliated Hospital, Sun Yat-Sen University  and Guangdong Provincial Key Laboratory of Orthopedics and Traumatology; Guangzhou, China

This work was supported by Russell Berrie Foundation (L.Q. and Q.W.), Blavatnik SIRS funding (L.Q. and   K.W.L.), National Institutes of Health grant RO1AR073935 and the U.S. Army Medical Research grant W81XWH1910463 (K.W.L.), and The Manoogian Simone Foundation (M.D.G).

COI: A patent application is pending. All other authors declare no conflict of interest.

Journal: Biomaterials

Title: “Polycationic PAMAM ameliorates obesity-associated chronic inflammation and focal adiposity.”

Authors: Baoding Huang (1,2), Qianfen Wan (3), Tianyu Li (2), Calhoun Carmen (3), Kam W. Leong (2), and Li Qiang (3)

  1. Department of Orthopaedic Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University and Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology, Guangzhou, China
  2. Department of Biomedical Engineering, Columbia University
  3. Naomi Berrie Diabetes Center and Department of Pathology and Cell Biology, Columbia University

The study was supported by the Russell Berrie Foundation (L.Q. and Q.W.), Blavatnik SIRS funding (L.Q. and   K.W.L.), National Institutes of Health grant RO1AR073935 and the U.S. Army Medical Research grant W81XWH1910463 (K.W.L.).

COI: The authors have patents pending. No other competing interests are declared.

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